MiR-1271 Inhibits Ovarian Cancer Growth by Targeting Cyclin G1
نویسندگان
چکیده
منابع مشابه
MiR-1271 Inhibits Ovarian Cancer Growth by Targeting Cyclin G1.
BACKGROUND Ovarian cancer is the most lethal gynecological malignant cancer in the female genital system. The dysfunction of miRNA contributes to ovarian cancer development. MATERIAL AND METHODS The miR-1271 level in ovarian cancer tissues and cells was assayed by qRT-PCR. The miR-1271 expression in cells was overexpressed by miRNA-mimic transfection and reduced by miRNA-antisense-oligonucleo...
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BACKGROUND It has been proposed that cyclin G1 (CCNG1) participates in p53-dependent G1-S and G2 checkpoints and might function as an oncogenic protein in the initiation and metastasis of ovarian carcinoma. MicroRNA 23b (miR-23b) is a critical regulatory factor in the progression of many cancer cell types that targets the relevant genes. METHODS MiR-23b expression in ovarian tissues was quant...
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ژورنال
عنوان ژورنال: Medical Science Monitor
سال: 2015
ISSN: 1643-3750
DOI: 10.12659/msm.895562